Bacillus Globigii Endospores Reduction

Authors
Jamie Balarashti, Zach Conley
Facility
Aerosol Research and Engineering Laboratories, Kansas
Download
Full Report

Objective

To evaluate the efficacy of the Defend 400 at reducing aerosolized Bacillus Globigii bacterial endospores a commonly used surrogate for Bacillus Anthraxis.

Methodology

Bacillus Globigii was aerosolized into a 16m3 sealed environmental bioaerosol chamber containing the Defend 400.

AGI impingers were used to sample the chamber bioaerosol concentrations. All impinger samples were serially diluted, plated and enumerated in triplicate to yield viable bioaerosol concentration at each sampling point and time. Samples were taken at 0, 15, 30, 45 and 60 minutes in order to quantify the reduction speed and capabilities of the Defend 400. Chamber control trial data was subtracted from the Defend 400 trial data to yield net LOG reduction in the chamber for the bioaerosol challenges.

This study was conducted in compliance with FDA Good Laboratory Practices (GLP) as defined in 21 CFR, Part 58.

Summary of Results

The Defend 400 achieved a net LOG reduction of Bacillus Globigii endospores after 45 minutes of 4.55 which is equivalent to a net percent reduction of 99.9969%.

Defend 400 achieved 99.99% reduction of Bacillus Globigii endospores

Contact

USA Headquarters
3540 Toringdon Way, Suite 200 Charlotte, NC  28277
1 866 508 1118
info@wellairsolutions.com

Ireland Headquarters
DCU Innovation Campus
Old Finglas Road
Glasnevin, Dublin D11 KXN4
+353 1 907 2750
info@wellairsolutions.com

Contact WellAir

Social

Partners